Fluidized Bed Granulator Equipped with Opposed Pulsed Jet Assembly.

Hydrodynamic Behavior of Particles in a Jet Flow of a Gas Fluidized Bed

Numerous investigations have been devoted towards understanding the hydrodynamics of gas jets in fluidized beds. However, most of them address the problem from  macroscopic point of view, which does not reveal the true behavior in the jet region at the single particle level. The present work aims to understand the jet behavior from a more fundamental level, i.e. the individual particle leve...

Effect of Process Variables on Growth Kinetics of Lactose Particles in a Wet Spray Fluidized Bed Granulator

Fluidized Bed Processing for Multiparticulates

World wide in pharmaceutical industry, fluid bed processing technology emerged as useful application. Batch type fluid processes are using in pharmaceutical industry since 30 years. Originating in Europe, this technology gradually found its way into U.S. manufacturing facilities, beginning with the use of fluid bed dryers. The earliest fluid bed dryers were a cabinet type construction with a si...

Batch grinding kinetics of Ethenzamide particles by fluidized-bed jet-milling.

Ethenzamide solids as a representative active pharmaceutical ingredient (API) were batch-ground by means of a fluidized-bed jet-mill which is a relatively new equipment and promising for production in the pharmaceutical field. Thus, the characteristic grinding mechanism was investigated. As a result, the variation of the residual ratio with grinding time after milling was expressed simply by a ...

Modeling Gas-Solids Entrainment into a Horizontal Gas Jet Submerged within a Fluidized Bed